Alpha-GPC improves cognitive function in mild to moderate Alzhemier's dementia.

By Gareth Jones

Abstract Title: Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-​blind, randomized, placebo-​ controlled trial. 

Abstract Source: Clin Ther. 2003 Jan;25(1):178-​-93. NCBI Public Medical Research PMID: 12637119

Abstract Author(s): Maria De Jesus Moreno Moreno

CONCLUSION: The results of this study suggest the clinical usefulness and tolerability of CA in the treatment of the cognitive symptoms of dementia disorders of the Alzheimer type.


Article Published Date: Jan 01, 2003

Alpha-gpc

Alpha-GPC

By Gareth Jones

CONCLUSION: The observation that treatment with choline alphoscerate attenuates the extent of glial reaction in the hippocampus of SHR suggests also that the compound may af ord neuroprotection in this animal model of vascular brain...

Alpha--GPC prevents scopolamine--induced learning impairment.

By Suzanne Francey

The data suggest that the behavioural effects of alpha-GPC may be related to its property to increase hippocampal ACh synthesis and release."