Alpha-GPC may increase the expression of Nerve Growth Factor receptors in the rat cerebellar cortex.
CONCLUSION: These results suggest that choline alfoscerate treatment may increase the expression of NGF receptors in the rat cerebellar cortex."
Alpha--GPC prevents scopolamine--induced learning impairment.
L-alpha-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the rat.
Eur J Pharmacol. 1992 Feb 18;;211(3):351-8. NCIB Public Medical Research PMID: 1319912
S Sigala, A Imperato, P Rizzonelli, P Casolini, C Missale, P Spano
The data suggest that the behavioural effects of alpha-GPC may be related to its property to increase hippocampal ACh synthesis and release."