Acetyl-l-carnitine and R-alpha-lipoic acid partially reverses brain decay and RNA/DNA oxidation associated with memory loss in rats.

By Gareth Jones

Abstract Source: Proc Natl Acad Sci U S A.2002 Feb 19;99(4):2356-​-61. PMID: 11854529

Abstract Author(s): Jiankang Liu, Elizabeth Head, Afshin M Gharib, Wenjun Yuan, Russell T Ingersoll, Tory M Hagen, Carl W Cotman, Bruce N Ames

CONCLUSION: These results suggest that feeding ALCAR and LA to old rats improves performance on memory tasks by lowering oxidative damage and improving mitochondrial function.


Article Published Date: Feb 19, 2002 

Acetyl- l-carnitine Alzheimer's disease

Acetyl-l-carnitine delays the mitochondrial decay of aging and improves cognitive function in Alzheimers disease.

By Gareth Jones

CONCLUSION: A recent meta-​-analysis of 21 double-​-blind clinical trials of acetyl carnitine in the treatment of mild cognitive impairment and mild Alzheimer's disease showed significant efficacy vs. placebo. A meta-​-analysis of 4 clinical trials of...
Acetyl- l-carnitine Alzheimer's disease

Acetyl-l-carnitine delays the mitochondrial decay of aging and improves cognitive function in Alzheimers disease.

By Gareth Jones

CONCLUSION: A recent meta-​-analysis of 21 double-​-blind clinical trials of acetyl carnitine in the treatment of mild cognitive impairment and mild Alzheimer's disease showed significant efficacy vs. placebo. A meta-​-analysis of 4 clinical trials of...